Insights from the Journey

Research, reflections, and the deeper why behind our work with psilocybin, breathwork, and body-oriented practices

Why Psychedelics Reach What Antidepressants Miss
psychedelics, psilocybin, depression, mental health Ioana and Imke . psychedelics, psilocybin, depression, mental health Ioana and Imke .

Why Psychedelics Reach What Antidepressants Miss

Why Psychedelics Reach What Antidepressants Miss

The brain in depression is not simply sad. It is structurally stuck — caught in self-reinforcing loops that conventional treatment can dampen but rarely dissolves. In this post, behavioral scientist and psychedelic facilitator Ioana goes into the neuroscience: what psychedelics actually do to large-scale brain organisation, why that is fundamentally different from how antidepressants work, and what it means in practice for people who haven't been helped by anything else. Part two of two.

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We Are in the Middle of a Depression Epidemic
psychedelics, depression, mental health, psilocybin Ioana and Imke . psychedelics, depression, mental health, psilocybin Ioana and Imke .

We Are in the Middle of a Depression Epidemic

We Are in the Middle of a Depression Epidemic. And Our Main Tool Is Not Enough

Depression affects hundreds of millions of people worldwide — but the full scale of the epidemic includes a much larger, quieter group who live with significant symptoms without ever receiving a diagnosis. In this post, behavioral scientist and psychedelic facilitator Ioana explores the limits of current antidepressant treatment, the growing evidence for psychedelics as a genuinely different approach, and why the mechanism matters as much as the outcome. Part one of two.

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